Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 44. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3163	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	22Rv1	40000 cells per well	NA	Cell proliferation kit 1 assay	0.01 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3164	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	22Rv1	40000 cells per well	NA	Cell proliferation kit 1 assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3165	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	22Rv1	40000 cells per well	NA	Cell proliferation kit 1 assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3166	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	22Rv1	40000 cells per well	NA	Cell proliferation kit 1 assay	10 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3167	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	40000 cells per well	NA	Cell proliferation kit 1 assay	0.01 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3168	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	40000 cells per well	NA	Cell proliferation kit 1 assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3169	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	40000 cells per well	NA	Cell proliferation kit 1 assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3170	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	40000 cells per well	NA	Cell proliferation kit 1 assay	10 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3171	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	40000 cells per well	NA	Calcein AM assay	0.01 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3172	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	40000 cells per well	NA	Calcein AM assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3173	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	40000 cells per well	NA	Calcein AM assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3174	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	40000 cells per well	NA	Calcein AM assay	10 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	28557974
OV_3175	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	NA	NA	NA	NA	NA	CAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6)	1.0E+6 pfu	NA	Complete regression in tumor volume after 20 days	Intraperitoneal	NA	NA	NA	28557974
OV_3176	Semliki forest virus	SFV-VA7	RNA	Togaviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	NA	NA	NA	NA	NA	CAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6)	1.0E+6 pfu	NA	Complete regression in tumor volume after 20 days	Intraperitoneal	NA	NA	NA	28557974
OV_5126	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5127	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5128	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5129	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	1 MOI	42% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5130	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5131	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5132	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	82% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5133	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.1 MOI	71% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5134	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	1 MOI	44% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5135	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5136	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5137	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.01 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5138	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.1 MOI	88% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5139	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5140	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5141	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.001 MOI	88% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5142	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5143	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	0.1 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5144	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5145	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	GL261	20000 cells per well	NA	MTS assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5146	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.001 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5147	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.01 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5148	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.1 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5149	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	1 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5150	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	10 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5151	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.001 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5152	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.01 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5153	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	0.1 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5154	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	1 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5155	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine glioma cell line	CT-2A	20000 cells per well	NA	MTS assay	10 MOI	5% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889